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Original Article
Clinical Significance of Serum ECP in Mycoplasma Pneumoniae Pneumonia
Young Ghil Rah, Dong Keun Lee, In Seok Lim, Eung Sang Choi, Soo Ahn Chae
Clin Exp Pediatr. 1999;42(5):672-678.   Published online May 15, 1999
Purpose : Allergic inflammation of the lower respiratory tract is a characteristic clinical feature in asthma patients, in which eosinophils play an important role. The activity of eosinophil may be determined by measuring the level of eosinophil cationic protein(ECP) in sputum or serum as a potential marker of the inflammatory severity. Methods : We measured the serum concentrations of ECP...
Clinical Utility of the Sputum Polymerase Chain Reaction Obtained by Nebulizer in the Diagnosis of Mycoplasma pneumoniae Pneumonia
Kye Nam Yoon, Sang Wook Park, Eui Ho Lee, Won Bae Lee, Kyung Tai Whang, Hee Jin Lee
Clin Exp Pediatr. 1999;42(3):348-354.   Published online March 15, 1999
Purpose : The polymerase chain reaction(PCR) has been used for the early diagnosis of mycoplasmal infections using various clinical samples. In this study, the clinical utility of sputum PCR through a new method was studied to diagnose mycoplasma pneumonia. Methods : One hundred nineteen pneumonic patients, ages ranging from 15 months old to 15 years old, were examined from Aug, 1997...
Significance of Polymerase Chain Reaction Test for Diagnosis of Mycoplasma pneumoniae Pneumonia
Hae-kyung Lim, Young-Hun Chung
Clin Exp Pediatr. 1999;42(2):173-179.   Published online February 15, 1999
Purpose : Mycoplasma pneumoniae is a common cause of lower respiratory disease, especially in children and young adults. The diagnosis, in most cases, is confirmed by serology. M. pneumoniae is difficult to culture because of its fastidious nature, and growth is too slow for diagnostic use. In this prospective study, the sensitivity and specificity of the PCR assay was evaluated...
Relationship between Chest Radiography and Cell-mediated Immunity in Mycoplasma pneumoniae Pneumonia
Yong Dae Ham, Jae Il Yoo, Jin Hwa Jeong, Jeong Ho Lee, Jong Dae Cho
Clin Exp Pediatr. 1998;41(11):1509-1516.   Published online November 15, 1998
Purpose : Mycoplasma pneumoniae pneumonias have been one of the most common causes of lower respiratory tract diseases during childhood. It is suggested that pathologic changes seen in the lung tissues were the histologic expression of the host immune response. The aim of this study was to determine the relationship between the chest radiographic pattern of Mycoplasma pneumoniae pneumonia and...
The Diagnostic Value of Polymerase Chain Reaction in Mycoplasma pneumoniae Pneumonia
Han Wook Kang, Byung Moon Ahn, Moo Young Song, Eun Ryoung Kim, Suk Ho Choi, Il Soo Kim
Clin Exp Pediatr. 1998;41(10):1351-1358.   Published online October 15, 1998
Purpose : This study was performed to evaluate the polymerase chain reaction(PCR) in the diagnosis of Mycoplasma pneumoniae pneumonia in comparison with the specific antibody test. Methods : Five hundred and ten patients with pneumonia, ranging from the ages of 8 months to 15 years who were admitted in Sung-Ae and Kwangmyung Sung-Ae general hospitals from Nov. 1996 to Oct....
Study of Seroprevalence of Antimycoplasma Antibody in Healthy Children and its Diagnostic Value
Soo Kyung Choi, Ji Ah Jung, Kyung Hyo Kim, Gyoung Hee Kim
Clin Exp Pediatr. 1998;41(4):489-497.   Published online April 15, 1998
Purpose : To evaluate the diagnostic reliability of the single serum titers of the specific serum antibody determiantion method, we compared antimycoplasma antibody titers of 177 healthy children with 353 children who had respiratory symptoms indicative of Mycoplasma pneumoniae infection. Methods : We used Serodia-Myco II particle agglutination test and the titers of ≥1:40 were regarded as positive. Results : Age distribution of 177 healthy...
Clinical Change of Mycoplasma Pneumonia
Jae Bum Lee, Kyong Tae Whang, Jeong Hyun Kim, Kyong Og Ko, Ji Hee Cho, Yun Duk Yoo
Clin Exp Pediatr. 1998;41(3):315-322.   Published online March 15, 1998
Purpose : It was noted some changes of clinical manifestations of mycoplasma pneumonia. we reviewed and compared these changes and saught any clues causes for proper dignosis and treatment. Methods : We divided patients with mycoplasma pneumonia into two groups, Group 1(from Jan. to Dec. 1996) and Group 2(from Jan. to Dec. 1994), and analyzed clinical, radiologic, and serologic differences. Results :...
Efficacy of Mycoplasma Antibody Test and Cold Agglutinin Test in the Diagnosis of Mycoplasma Pneumonia in Children
Jung Ae Son, Weon Par, Dong Jin Lee
Clin Exp Pediatr. 1998;41(2):179-185.   Published online February 15, 1998
Purpose : This study was done to compare the diagnostic value of the Mycoplasma antibody (M- Ab) test and the cold agglutinin(CA) test from the onset of Mycoplasma pneumoniae pneumonia to its diagnosis in children. Methods : We analyzed 48 cases of M. pneumoniae pneumonia in children who were admitted to the Pediatric Department of Ulsan Dongkang General Hospital for 1...
Occurrence of Mycoplasma pneumoniae Pneumonia in Seoul, Korea, from 1986 to 1995
Jung-Yun Hong, Song-Yi Nah, Seung-Gon Nam, Eun-Hwa Choi, Jin-Young Park, Hoan-Jong Lee
Clin Exp Pediatr. 1997;40(5):607-613.   Published online May 15, 1997
Relationship between Complications of Mycoplasma Pneumonia and Titers of Cold Agglutinin and Mycoplasma Antibody in Children
Sung Soo Rim, Myung Hyun Cho, Byung Min Moon, Kyoung Sim Kim, Kibok Kim
Clin Exp Pediatr. 1996;39(12):1680-1689.   Published online December 15, 1996
Purpose : To assess the relationship between the complications of mycoplasma pneumonia and titers of cold agglutinin and mycoplasma antibody in children. Methods : 120 cases of mycoplasmal pneumonia in children who were admitted to the Pediatric Department of Kwangju Christian Hospital between June 1993 and May 1994 were analyzed. Results : 1) The peak incidence of age was between 2 and...
Genital Mycoplasmasin the Newborn Infants: Colonization, Prevalence and Clinical Significance
Yun Sil Chang, Sung Gwon Kim, Beyong Il Kim, Won Soon Park, Bo Hyun Yoon, Eui Chong Kim, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1996;39(8):1084-1094.   Published online August 15, 1996
Purpose : The genital mycoplasmas: Ureaplasma urealyticum and Mycoplasma hominis have recently assumed an increasing importance as neonatal pathogens especially in preterm infants. The aim of the present study was to determine the prevalence of infections with these organisms in newborn infants who were admitted in Neonatal Intensive Care Unit(NICU) and who were suspected having infection in newborn nursery Methods : Sixty four inborns who...
Cold Agglutinin and Mycoplasma Antibody Titersin Children with Mycoplasma pneumoniae Pneumonia During Recent 5 Years
Seon Hwa Yoon, Joon Kyo Jung, Myung Ho Oh
Clin Exp Pediatr. 1996;39(7):943-952.   Published online July 15, 1996
Purpose : More effective diagnosis and treatment through a survey on clinical aspect for the last 5 years and interrelation between cold agglutinin titer and mycoplasma antibody titer of Mycoplasma pneumoniae pneumonia. Methods : 369 patients hospitalized in the department of pediatrics of Chung Goo Sung Shim Hospital for the 5 years from January 1990 to December 1994 have been surveyed, which diagnosed to be...
Neurologic Complications Associated with Mycoplasma pneumoniae Infection
Sung-Jong Park, Tae-Sung Ko, Hyung-Nam Moon, Chang-Yee Hong
Clin Exp Pediatr. 1996;39(3):346-353.   Published online March 15, 1996
Purpose : Mycoplasma pneumoniae is known to be a common respiratory pathogen in children and cause neurologic complications in some patients. The clinical spectrum of the neurologic complications is wide, ranging from mild meningeal signs to severe neurologic symptoms with poor outcomes. The overall mortality in patients with neurologic complications has been approximated upto 10% and significant residual deficits could...
Case Report
A Case of Cerebral Infarction Associated with Mycoplasma pneumoniae Infection
Young Jae Koh, Dong Jun Kim, In Joon Seol, Ha Baik Lee, Ki Woong Hong
Clin Exp Pediatr. 1996;39(1):115-119.   Published online January 15, 1996
Mycoplasma pneumoniae has been shown to be of etiologic importance in cases of upper-and lower-respiratory tract infections, especially in children and young adults. It may cause a variety of extrapulmonary manifestations in multiple organ systems, most commonly the central nervous system. The extrapulmonary syndromes include meningitis, cerebral infarction, acute transverse myelitis, psychosis, cerebellar ataxia, Guillain-Barré syndrome and Reye syndrome. Cerebral...
Original Article
A Study of Relationship between Bronchial Hyperreactivity (BHR) and Atopic Findings in Mycoplasma pneumoniae Pneumonia
In Kyeong Seo, Weon Jeong Bae, Jae Ook Lee, Im Ju Kang
Clin Exp Pediatr. 1995;38(9):1210-1219.   Published online September 15, 1995
Purpose : The respiratory infection due to Mycoplasma pneumoniae among school aged children and adolescents was recognized as an important cause of wheezing or BHR. This study was performed to evaluate relationship between BHR to Mch inhalation challenge and atopic findings in M. pneumoniae pneumonia. Methods : 61 patients with M. pneumoniae pneumonia who were admitted to the department of Pediatrics,...
Detection of Mycoplasma pneumoniae in clinical Samples from Pediatric Patients by Polymerase Chain Reaction
Baik-Lin Eun, Sang Hee Park, Young Chang Dockgo, Sang Chul Seong
Clin Exp Pediatr. 1995;38(8):1077-1086.   Published online August 15, 1995
Purpose : Mycoplasma pneumoniae is a common cause of a wide rage of upper and lower respiratory tract infections, especially in children and young adults. Routine laboratory diagnosis of M.pneumoniae infection is based mainly on serology and, to lesser extent, on cultivation. The cultivation of M.pneumoniae, a fastidious microorganism, is time-consuming and may require 1-3 weeks for results. Serological procedures...
Case Report
One Case of Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome due to Mycoplasma pneumoniae In fection
Soo Kyung Lee, Joon Soo Lee, Soo Young Lee, Byung Ju Jeoung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1993;36(10):1441-1446.   Published online October 15, 1993
Bronchiolitis obliterans is an infrequent disorder characterized by partial or complete obstruction of bronchi and bronchioles by fibrous tissue following an insult to the lower respiratory tract. In the pediatric population, Bronchiolitis obliterans has most frequently been preceded by respiratory tract infection by adenovirus, influenza, measles. But it may occur in young adults after mycoplasma infection. We experienced the case...
Original Article
A Clinical Study on Wheezing of Mycoplasma Pneumoniae Pneumonia in Children
Jeong Eun Kwon, Jun Ho Yoon, Jae Ook Lee, Im Ju Kang
Clin Exp Pediatr. 1993;36(10):1366-1374.   Published online October 15, 1993
The relationship between respiratory infections and exacerbations of wheezing in patients with wheezy bronchitis or asthma has been described. Most respiratory infections were viral or Mycoplasma pneumoniae. This study was performed to evaluate the effect of Mycoplasma pneumoniae infection on bronchial reactivity and atopic background. 106 patients with Mycoplasma pneumoniae pneumonia who were admitted to the department of pediatrics, Fatima Hospital,...
Clinical Consideration between the Type of pneumonia and cold Agglutinin Titer, and Mycoplasma Antibody Titer caused by Mycoplasma pneumonia in Children
Byung Yeon Kim, Hyang Suk Lee, Ill Kyung Kim, Chang Hee Choi, Jyung Ho You
Clin Exp Pediatr. 1993;36(7):959-967.   Published online July 15, 1993
The authors analysed 261 cases of mycoplasmal pneumonia in chidren who were admitted to the pediatric department of Seoul Adventist Hospital between July 1986 and June 1991. The result obtained were as follows; 1) Yearly distribution of the cases showed high in 1987 and 1991, but no significant difference was noted in seasonally or monthly distribution. 2) The peak incidence of age was...
A Clinical Study of Mycoplasma Pneumonia in Children During Recent 5 Years
In Seung Park, Ha Baik Lee
Clin Exp Pediatr. 1992;35(8):1082-1088.   Published online August 15, 1992
Mycoplasma pneumoniae infections are among the most frequent respiratory diseases of school-aged children, adolescents and young adults. However in preschool children a persistent nonproductive cough, fever and interstitial or lobular infiltrates on the chest radiograph can recently be recognized as presenting features of M. pneumoniae. We studied to find out the recent trends in epidermiologic and clinical variabilities of M. pneumoniae...
Clinical Study of Mycoplasmal Pneumonia Syndrome in Children
Hyeon-Hi Kim, Hung-Ki Min, Seung-Hoon Han, Jin-Han Kang, Joon-Sung Lee, Sung-Hoon Cho
Clin Exp Pediatr. 1992;35(4):451-458.   Published online April 15, 1992
Between September 1, 1989 and August 31, 1990, we studied 142 cases of mycoplasmal p neumonia syndrome in children who were admitted to the pediatric department of Catholic University Medical College. The results were as follows; 1) The highest incidence was in the age of 6 years in 27 cases and the male to female ratio...
The diagnosis of mycoplasma pneumoniae pneumonia by high density composite particles agglutinin test.
Hae Jin Choeh, Jung Hae Park, Chong Sung Chung, Kyu Chul Choeh
Clin Exp Pediatr. 1991;34(8):1102-1109.   Published online August 31, 1991
In a prospective investigation of 21 chi Idem 3 years of age or more with Mycoplasma pneumoniae pneumonia, we analyzed the diagnostic efficacy of High Density Composite Particles Agglutinin(HDDA) test comparing with cold agglutinin tests and clinical findings. The results obtained were as followed. 1) Among 24 total cases, the number of cases showing positive reaction to HDPA and to cold agglutination test were 17 and...
A clinical study of pneumonia presented with positive cold agglutin- in test.
Il Jung Joo, Jin Seop Juong, Sang Woo Kim
Clin Exp Pediatr. 1991;34(8):1093-1101.   Published online August 31, 1991
A clinical study was performed on 65 patients with Mycoplasma pneumoniae pneumonia who were admitted to the Department of Pediatrics of Seoul Paik hospital from September 1,1989 to August 31, 1990. The results were as follows; 1) Seasonal distribution showed a high frequency in summer (33 cases; 50.8%). 2) The peak incidence was 5 to 9 years of age (32cases;49.2%). 3) Male to female ratio was 1:1.17(30:35). 4) On the chest...
A case of pancytopenia associated with mycoplasmal pneumonia.
Young Mee Yoo, Beom Soo Park, In Sang Jeon, Hee Young Shin, Hyo Seop Ahn, Se Jung Sohn
Clin Exp Pediatr. 1991;34(6):826-831.   Published online June 30, 1991
Mycoplasma pneumoniae infection is manifestated as pneumonia and extra-pulmonary symptoms such as hematologic, neurologic, gastrointestinal, musculoskeletal, dermatologic and cardiac manifes- tations. Among the hematologic changes, hemolytic anemia is most frequently seen. Throm- bocytopenic purpura, lymphocytosis or rarely lymphopenia, elevated erythrocyte sedimentation rate, positive direct Coombs test, reticulocytosis and DIC are known hematologic features. This 12 years old female patient was presented with pneumonia and pancytopenia....
Clinical Study of Mycoplasma Pneumoniae Infection in Children.
Jong Woon Choi, Hoan Jong Lee, Byung Kiu Park, Hyung Ro Moon
Clin Exp Pediatr. 1990;33(3):315-323.   Published online March 31, 1990
A retrospective analysis of clinical findings in 43 patients with M. pneumoniae infection who visited Department of Pediatrics of Seoul National University Hospital from January, 1987 till December, 1987 was performed. 1) The peak incidence of age was 5 to 9 years of age (20 cases; 46.5%), and male-to-female ratio was 1.05:1. 2) Monthly distribution showed a high frequency in April (10 cases; 23.3%) and seasonal distribution showed...
Unusual Forms of Pulmonary and Extrapulmonary Manifestations of Mycoplasmal Pneumonia.
Young Soo Lee, Chang Ho Hong, Chul Lee, Sung Gyu Lee
Clin Exp Pediatr. 1989;32(8):1064-1073.   Published online August 31, 1989
A clinical study was performed on 145 patients admitted to the Departement of Pediatrics, Yong Dong Severance Hospital between July, 1984 and June, 1987 with the diagnosis of Mycoplasmal pneumonia. This diagnosis was done when chest X-ray or auscultation of the chest showed signs of pneumonia. Patients with cold agglutinin titrations of 1:64 or titrations with four fold increase during follow up had Indirect...
Clinical Study of Interrelationship Between Cold Agglutinin Titers and Indirect Hemagglutination Titers in Children with Mycoplasma Pneumoniae Pneumonia During Recent 3 Years.
Jong Chan Shin, Jae Youn Kim, Myung Ik Lee, Soon Wha Kim, Keun Chan Sohn, Kyeung Eun Jung
Clin Exp Pediatr. 1989;32(7):915-925.   Published online July 31, 1989
A clinical study was made on 103 cases of Mycoplasma pneumoniae pneumonia patients during the period of 3 years from July ’84 to June '87. Indirect hemagglutination test (IHA) and/or cold agglutinin test (CAT) were measured and follow-up studies were done until the 50th day of the illness. Each titer was compared for analysis of interrelationship between them. And we obtained following results: 1) The highest...
A Case of Mycoplasmal Meningitis Associated with Mycoplasma Pneumoniae Pneumonia.
Sang Young Jeong, Seung Koog Kim, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(4):556-560.   Published online April 30, 1989
Mycoplasmas have been recognized as pathogens of respiratory tract in children and adolescence, but clinically apparent pneumonia develops in only 3 to 10% of infected persons. Central nervous system complication, such as aseptic meningitis, meningoencephalitis. transverse myelitis, hemiplegia, cerebellar ataxia and psychosis, associated with Mycoplasma pneumoniae infection were developed in .0.1 % of all Mycoplasmal infection. We experienced a case of Mycoplasma pneumoniae pneumonia and...
Clinical Consideration on Pneumonia caused by Mycoplasma Pneumoniae in Children.
Il Kyung Kim, Hyung Jin Kwon, Ho Seong, Chang Hee Choi
Clin Exp Pediatr. 1989;32(1):1-10.   Published online January 31, 1989
A retrospective analysis of clinical findings in 63 patients above 2 years of age who were admitted to our hospital due to pneumonia caused by Mycoplasma pneumoniae from July, 1986 to June, 1987 was performed. The results obtained were as follows: 1) The number of patients showing positive reaction to cold agglutinin test (above 1:64) were 59 (55. 7%) among 106 total pneumonia cases. 2) The...
A Clinical Study of Mycoplasma Pneumoniae Pneumonia.
Jeong Wi Yook, Sun Ock Kim, Min Shik Kim, Hey Sun Lee, Young Min Ahn, Dae Young Kim
Clin Exp Pediatr. 1988;31(12):1603-1611.   Published online December 31, 1988
A clinical study was made on 114 cases of Mycoplasma pneumoniae pneumoniae pneumonia during the period of 3-6/12 years from April, 84 to September, 87. The results were as follows; 1) Among the 920 cases of lower respiratory tract infections, the incidence of Mycoplasma infection was 25.4%(234/920). 2) The mean age was 6.2 ±2.9 years and the male to female ratio was 1:1.1. 3) There was no significant seasonal...
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